[Plasma renin and erythropoietic activity following a decrease in extracellular volume]

A reduction of the extracellular volume of the peritoneal dialysis in rats induced modifications in plasma renin activity, plasma erythropoietic activity, and in renin activity in the renal cortex. A significant increase in the renin and erythropoietic activity was revealed in the experimental animals. It is assumed that renin and erythropoietin could be regarded as two links of the same broad control system, responsible for optimum tissue oxygen supply.