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Ultrastructure of endometrial epithelial cells in a three-dimensional cell culture system for human implantation
U Bentin-Ley1, S Lindenberg, T Horn
1Department of Obstetrics-Gynecology, Herlev Hospital, University of Copenhagen, Denmark.
Journal of Assisted Reproduction and Genetics
|October 1, 1995
Abstract
Purpose:
A three-dimensional cell culture system imitating normal uterine endometrium has previously been established. To what degree do cultured epithelial cells retain their morphological characteristics as compared to in vivo material obtained simultaneously from the same tissue donor.
Results:
We found a high degree of similarity between the in vivo and in vitro situations. The present culture system furthermore imitates the day-to-day morphology of the cycle.
Conclusions:
This indicates, that a correct timing of the biopsy tissue is important for future human implantation studies.