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Aquareovirus interference mediated resistance to infectious hematopoietic necrosis virus
S E LaPatra1, K A Lauda, G R Jones
1Clear Springs Foods Inc., Buhl, ID 83316, USA.
Veterinary Research
|January 1, 1995
Abstract:
This study investigated the stimulation of specific host defenses to IHNV that are created by prior exposure to an avirulent reovirus (chum salmon reovirus; CSV). Preexposure of rainbow trout to CSV for 1 h resulted in a relative percent survival that ranged from 68 to 100% when fish were challenged with IHNV over an 8 week period. The levels of serum neutralizing antibodies detected 28 d after the IHNV challenge were significantly lower among fish receiving prior exposures to CSV than among non-CSV-treated fish. The differences in the humoral response to IHNV in the CSV-treated fish suggested that other immune defense mechanisms may be involved.