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Preparation and pharmacological evaluation of 1-(1,4-benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes as potent
K Suzuki1, T Tatsuoka, T Ishihara
1Suntory Institute for Biomedical Research, Osaka, Japan.
Chemical & Pharmaceutical Bulletin
|January 1, 1996
Abstract:
Two new series of 1-(1,4-benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes (3,4) were synthesized for evaluation of their pharmacological activities. These compounds showed significant anti-lipid peroxidation (ALP) activities with rat brain homogenate and some of them possessed a protective effect against hypobaric hypoxia in mice.