Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

DNA fingerprinting for forensic identification: some statistical issues

P P Majumder1

  • 1Anthropometry and Human Genetics Unit, Indian Statistical Institute, Calcutta, India.

Electrophoresis
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kalyani cohort - the first platform in Eastern India for longitudinal studies on health and disease parameters in peri-urban setting.

Global health, epidemiology and genomics·2018
Same author

WITHDRAWN: Association of uncoupling protein 2 and 3 gene polymorphisms with type 2 diabetes in Asian Indians.

Journal of endocrinological investigation·2009
Same author

Portability of tag SNPs across isolated population groups: an example from India.

Annals of human genetics·2007
Same author

Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians.

Diabetic medicine : a journal of the British Diabetic Association·2007
Same author

Remarkable variation in the informativeness of RFLP markers linked to hemophilia B locus in Indian population groups: implication in the strategy for carrier detection.

Disease markers·2007
Same author

Evidence of linkage and association on 18p11.2 for psychosis.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics·2006
Same journal

Kinship Inferences for Second-Degree Relatives With a Combination of STRs and Microhaplotypes.

Electrophoresis·2026
Same journal

Optimisation of Electrokinetic Extraction System: Colourimetric Determination of Copper (II) in Sand Using Polymer Inclusion Membrane.

Electrophoresis·2026
Same journal

Novel Phloroglucinol Derivatives as Neuraminidase Inhibitors Identified From Humulus lupulus L. Extract by At-Line Nanofractionation Platform.

Electrophoresis·2026
Same journal

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles.

Electrophoresis·2026
Same journal

Dynamics of Heparin Translocations Through Solid-State Nanopores.

Electrophoresis·2026
Same journal

Production of Protein Hydrolysates and Bioactive Peptides From Lablab purpureus and Macrotyloma uniflorum via Optimized Extraction and Proteolysis Protocols.

Electrophoresis·2026
See all related articles

This study introduces improved statistical methods for DNA fingerprinting, addressing correlated measurement errors in fragment lengths. The new elliptical match windows enhance forensic identification accuracy compared to current linear methods.

Area of Science:

  • Forensic Science
  • Statistical Genetics
  • Molecular Biology

Background:

  • DNA fingerprinting relies on fragment length analysis.
  • Current methods inadequately address correlated measurement errors in fragment lengths, which are proportional to length.
  • Existing matching procedures often ignore these error correlations.

Purpose of the Study:

  • To develop a statistical model and techniques addressing correlated measurement errors in DNA fragment lengths.
  • To improve the accuracy of forensic identification in DNA fingerprinting.
  • To propose new matching procedures that utilize empirical observations of measurement errors.

Main Methods:

  • Development of a statistical model based on empirical observations of fragment length measurement errors.

Related Experiment Videos

  • Introduction of elliptical match windows to replace traditional linear windows.
  • Simulation experiments to compare the proposed procedure with current methods.

    • Main Results:

    • The proposed procedure, using elliptical match windows, demonstrates superior performance over current methods.
    • The new technique effectively utilizes the correlated nature of measurement errors.
    • The procedure relaxes some underlying assumptions of existing DNA matching techniques.

    Conclusions:

    • The proposed statistical model and elliptical match windows offer a more accurate approach to DNA fingerprinting and forensic identification.
    • This method provides a significant improvement by properly accounting for measurement error correlations.
    • The procedure is extendable to incorporate replicate measurements for enhanced reliability.