Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Why ontogeny recapitulates phylogeny

S Ohno1

  • 1Beckman Research Institute of the City of Hope, Duarte, CA 91010-3000, USA.

Electrophoresis
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Genes persist through evolution, influencing embryonic development and even reappearing after long dormancy. This explains developmental patterns and genetic "resurrections" observed in species like primates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary structure of a gamma subunit of G protein, gamma 12, and its phosphorylation by protein kinase C.

The Journal of biological chemistry·1995
Same author

Two types of aminoacyl-tRNA synthetases could be originally encoded by complementary strands of the same nucleic acid.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life·1995
Same author

The genetic link between the Chinese bamboo partridge (Bambusicola thoracica) and the chicken and junglefowls of the genus Gallus.

Proceedings of the National Academy of Sciences of the United States of America·1995
Same author

Neutrophil inhibitory factor prevents neutrophil-dependent lung injury.

Journal of immunology (Baltimore, Md. : 1950)·1995
Same author

Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome.

Proceedings of the National Academy of Sciences of the United States of America·1995
Same author

Differential targeting of protein kinase C and CaM kinase II signalings to vimentin.

The Journal of cell biology·1995
Same journal

Kinship Inferences for Second-Degree Relatives With a Combination of STRs and Microhaplotypes.

Electrophoresis·2026
Same journal

Optimisation of Electrokinetic Extraction System: Colourimetric Determination of Copper (II) in Sand Using Polymer Inclusion Membrane.

Electrophoresis·2026
Same journal

Novel Phloroglucinol Derivatives as Neuraminidase Inhibitors Identified From Humulus lupulus L. Extract by At-Line Nanofractionation Platform.

Electrophoresis·2026
Same journal

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles.

Electrophoresis·2026
Same journal

Dynamics of Heparin Translocations Through Solid-State Nanopores.

Electrophoresis·2026
Same journal

Production of Protein Hydrolysates and Bioactive Peptides From Lablab purpureus and Macrotyloma uniflorum via Optimized Extraction and Proteolysis Protocols.

Electrophoresis·2026
See all related articles

Area of Science:

  • Developmental Biology
  • Evolutionary Genetics
  • Comparative Embryology

Background:

  • Embryonic development in mammals involves sequential formation of structures like the notochord, somites, and kidneys (pronephros, mesonephros, metanephros).
  • Ernst Haeckel's dictum, "ontogeny recapitulates phylogeny," suggests developmental stages reflect evolutionary history.
  • The persistence of genes, even after their original function is lost, is a key factor in this phenomenon.

Purpose of the Study:

  • To explore the evolutionary persistence of genes and their role in embryonic development.
  • To investigate the concept of genetic "resurrection" and its implications for evolutionary theory.

Main Methods:

  • Comparative analysis of gene function across different species and developmental stages.

Related Experiment Videos

  • Examination of genetic mechanisms underlying embryonic development.
  • Review of existing literature on gene persistence and evolutionary developmental biology.

    • Main Results:

    • Genes can remain dormant for extended periods but retain their potential for expression.
    • The "immortality" of genes explains why ancestral developmental pathways are recapitulated.
    • Examples include genes for chicken dental enamel and resurrected opsin genes in primates.

    Conclusions:

    • Gene persistence is a fundamental driver of evolutionary developmental biology.
    • Recapitulation in ontogeny is largely explained by the enduring nature of the genome.
    • The potential for gene resurrection highlights the dynamic and adaptable nature of evolution.