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[Infections in diabetes mellitus]

S Schubert1, J Heesemann

  • 1Institut für Hygiene und Mikrobiologie, Universität Würzburg.

Immunitat Und Infektion
|December 1, 1995
PubMed
Summary
This summary is machine-generated.

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Diabetes mellitus (DM) increases infection risk due to impaired immune cell function. Managing blood sugar, hygiene, and vaccinations can prevent or lessen severe infections in diabetic patients.

Area of Science:

  • Endocrinology
  • Immunology
  • Infectious Diseases

Context:

  • Diabetes mellitus is a common metabolic disorder.
  • Diabetic patients exhibit impaired immune cell function, particularly phagocytes like polymorphonuclear leucocytes.
  • Specific infections like skin/soft tissue infections, mucormycosis, otitis externa, and UTIs are prevalent in diabetes.

Purpose:

  • To highlight the link between diabetes mellitus and increased susceptibility to infections.
  • To detail the immune dysfunctions characteristic of diabetic patients.
  • To outline common infections and their management in diabetes.

Summary:

  • Diabetes mellitus predisposes individuals to infections due to compromised phagocyte function.
  • Common infections include skin and soft tissue infections, mucormycosis, invasive external otitis, and urinary tract infections.

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  • Effective management involves strict metabolic control, hygiene, vaccination, and prompt antimicrobial therapy, potentially including surgical intervention.

    • Impact:

    • Understanding these associations aids in preventing severe infections in diabetic populations.
    • Highlights the importance of comprehensive patient care, including infection prevention strategies.
    • Informs clinical practice regarding the recognition and management of infections in patients with diabetes mellitus.