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[Infections in diabetes mellitus]

S Schubert1, J Heesemann

  • 1Institut für Hygiene und Mikrobiologie, Universität Würzburg.

Immunitat Und Infektion
|December 1, 1995
PubMed

Insights

Diabetes mellitus (DM) increases infection risk due to impaired immune cell function. Managing blood sugar, hygiene, and vaccinations can prevent or lessen severe infections in diabetic patients.

Area of Science:

  • Endocrinology
  • Immunology
  • Infectious Diseases

Context:

  • Diabetes mellitus is a common metabolic disorder.
  • Diabetic patients exhibit impaired immune cell function, particularly phagocytes like polymorphonuclear leucocytes.
  • Specific infections like skin/soft tissue infections, mucormycosis, otitis externa, and UTIs are prevalent in diabetes.

Purpose:

  • To highlight the link between diabetes mellitus and increased susceptibility to infections.
  • To detail the immune dysfunctions characteristic of diabetic patients.
  • To outline common infections and their management in diabetes.

Summary:

  • Diabetes mellitus predisposes individuals to infections due to compromised phagocyte function.
  • Common infections include skin and soft tissue infections, mucormycosis, invasive external otitis, and urinary tract infections.
  • Effective management involves strict metabolic control, hygiene, vaccination, and prompt antimicrobial therapy, potentially including surgical intervention.

Impact:

  • Understanding these associations aids in preventing severe infections in diabetic populations.
  • Highlights the importance of comprehensive patient care, including infection prevention strategies.
  • Informs clinical practice regarding the recognition and management of infections in patients with diabetes mellitus.

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