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Neuropharmacological effects of ivermectin in mice
1Department of Pharmacology & Toxicology, College of Veterinary & Animal Sciences, HPKV, Palampur.
Indian Journal of Physiology and Pharmacology
|October 1, 1995
Abstract:
Neuropharmacological effects (Spontaneous locomotor activity, forced locomotor activity and anticonvulsant activity) of invermectin were studied at 400, 800 and 1600 micrograms/kg (administered, subcutaneously). Spontaneous locomotor activity was reduced at all the dose levels but forced locomotor activity was slightly reduced at 800 and 1600 micrograms/kg. The drug did not exhibit any anticonvulsant potential at any of the dose levels studied.