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Infantile digital fibromas

N A Falco1, J Upton

  • 1Division of Plastic Surgery, New England Deaconess Hospital, Harvard Medical School, Boston, MA, USA.

The Journal of Hand Surgery
|November 1, 1995
PubMed
Summary
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Infantile digital fibromas are distinct pediatric lesions appearing early in life on the fingers. These rapidly growing tumors have unique histological features and may recur after treatment.

Area of Science:

  • Pediatric Dermatology
  • Oncology
  • Pathology

Background:

  • Infantile digital fibromas are rare, benign fibrous tumors affecting infants.
  • These lesions present unique clinical and histological characteristics.
  • Their etiology remains unclear, with viral causes unproven.

Purpose of the Study:

  • To describe the clinical presentation, histological findings, and management of infantile digital fibromas.
  • To differentiate infantile digital fibromas from other pediatric digital masses.
  • To highlight the potential for recurrence despite treatment.

Main Methods:

  • Case series presentation of 15 lesions in 8 pediatric patients.
  • Clinical data collection including age of onset, location, and growth pattern.

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  • Histopathological examination focusing on dermal origin and inclusion bodies.

    • Main Results:

    • Lesions typically occur on the ulnar three digits at interphalangeal joints, showing rapid growth.
    • Histology reveals deep dermal origin and unique intracytoplasmic inclusion bodies.
    • Recurrence was observed even after wide excision and reconstructive surgery.

    Conclusions:

    • Infantile digital fibromas are a unique pediatric condition with no adult equivalent.
    • Early diagnosis and consideration in the differential of pediatric digital masses are crucial.
    • The potential for recurrence necessitates careful follow-up and management strategies.