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Related Experiment Videos

AIDS-associated intussusception in young adults

B J Wood1, P N Kumar, C Cooper

  • 1Department of Radiology, Georgetown University Medical Center, Washington, D.C. 20007, USA.

Journal of Clinical Gastroenterology
|September 1, 1995
PubMed
Summary

Human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) are risk factors for adult intussusception. Consider intussusception in young, HIV-positive adults with abdominal pain.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Radiology

Background:

  • Adult intussusception is uncommon, with varied causes.
  • Human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) can cause gastrointestinal pathology.
  • Gastrointestinal pathology may act as a lead point for intussusception.

Purpose of the Study:

  • To examine the demographics of adult intussusception.
  • To investigate the association between HIV/AIDS and adult intussusception.
  • To highlight the role of computed tomography (CT) in diagnosing intussusception in HIV-positive patients.

Main Methods:

  • Retrospective review of eight adult intussusception cases over 10 years.
  • Analysis of diagnostic CT scans, clinical history, surgical findings, laboratory results, and pathology.

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  • Review of five previously reported cases of AIDS and intussusception.

    • Main Results:

    • Three of eight adult intussusception patients had AIDS, diagnosed by CT.
    • Average age of HIV-associated intussusception patients was 41 years, compared to 63 for non-HIV-associated cases.
    • CT scans effectively diagnosed intussusception in AIDS patients.

    Conclusions:

    • HIV/AIDS-associated gastrointestinal pathology is a significant risk factor for intussusception in young adults.
    • Intussusception should be considered in HIV-positive young adults presenting with abdominal pain.
    • CT is an effective diagnostic tool for AIDS-associated intussusception.