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Thyroidectomy for large multinodular colloid goitre

K R Gardiner1, C F Russell

  • 1Department of Endocrine Surgery, Royal Victoria Hospital, Belfast, UK.

Journal of the Royal College of Surgeons of Edinburgh
|December 1, 1995
PubMed
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This study on large multinodular colloid goitres found total thyroidectomy effective. Complete resection is recommended for significant goitres to manage symptoms and prevent recurrence.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Head and Neck Surgery

Background:

  • Multinodular colloid goitres can become significantly large, impacting patient health.
  • Large goitres may present with compressive symptoms affecting respiration and swallowing.
  • Surgical intervention is often necessary for symptomatic or very large goitres.

Purpose of the Study:

  • To evaluate the outcomes of surgical resection for large multinodular colloid goitres.
  • To assess the safety and efficacy of total thyroidectomy in managing these large goitres.
  • To determine the complication rates associated with thyroidectomy for massive goitres.

Main Methods:

  • A retrospective review of 474 thyroidectomies performed between 1983 and 1993.
  • Identification of 64 patients (14%) who underwent resection of multinodular colloid goitres weighing over 100 g.

Related Experiment Videos

  • Analysis of preoperative symptoms, radiographic findings, surgical procedures, and postoperative complications.

    • Main Results:

    • Preoperative symptoms included respiratory difficulty (42%) and dysphagia (22%).
    • Radiographic evidence of tracheal deviation (70%) and compression (42%) was common.
    • No perioperative mortality occurred; complications included permanent vocal cord paralysis (1.7%) and hypoparathyroidism (3.1%).

    Conclusions:

    • Total thyroidectomy is a safe and effective treatment for large multinodular colloid goitres.
    • Complete resection addresses compressive symptoms and reduces the risk of recurrence.
    • Surgical management should be considered for patients with massive goitres.