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Updated: Aug 15, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Anti-MI-2 antibody as a specific marker of dermatomyositis]
E Kowalska-Oledzka1, M Jarzabek-Chorzelska, Z Kołacińska-Strasz
1Zespołu Badawczo-Leczniczego Chorób Nerwowo-Mieśniowych, Instytutu Centrum Medycyny Doświadczalnej i Klinicznej PAN.
Abstract:
Anti-Mi-2 antibody directed against the protein complex of unknown function is considered an immunological marker of dermatomyositis. We detected this antibody in 7 among 72 patients, whose sera were investigated for the presence of myositis specific autoantibodies with the use of indirect immunofluorescence and double immunodiffusion. Six patients had dermatomyositis, and 1 had unclassified collagenosis. Detection of anti-Mi-2 antibody is very important for diagnosis because of its high specificity, and also for prognosis and therapy.
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