Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Drug-nutrient interactions

J A Thomas1

  • 1University of Texas, Health Science Center at San Antonio 78284-7722, USA.

Nutrition Reviews
|October 1, 1995
PubMed
Summary
This summary is machine-generated.

Drug efficacy is influenced by nutrition status, impacting pharmacodynamics. Special conditions and food interactions, especially in geriatric patients, can alter drug effectiveness and pharmacokinetics.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative losses of British butterflies, birds, and plants and the global extinction crisis.

Science (New York, N.Y.)·2004
Same author

Effect of room illuminance on monitor black level luminance and monitor calibration.

Journal of digital imaging·2004
Same author

Markedly elevated serum biotinidase activity may indicate glycogen storage disease type Ia.

Journal of inherited metabolic disease·2004
Same author

Genetic and clinical characterization of patients with an interstitial duplication 15q11-q13, emphasizing behavioral phenotype and response to treatment.

American journal of medical genetics. Part A·2003
Same author

Seasonal variation in the niche, habitat availability and population fluctuations of a bivoltine thermophilous insect near its range margin.

Oecologia·2003
Same author

Controlling substitution chemistry in ruthenium(II) systems. Synthesis of heteroleptic complexes incorporating the [Ru([9]aneS3)]2+ metal center.

Inorganic chemistry·2003
Same journal

Natural Approaches to Appetite Suppression in Obesity: Mechanisms, Evidence, and Clinical Integration.

Nutrition reviews·2026
Same journal

The Effect of Long-Chain Omega-3 Polyunsaturated Fatty Acid Supplementation on Neuromuscular Function in Humans: A Systematic Review with Narrative Synthesis.

Nutrition reviews·2026
Same journal

Oats in Gluten-Free Diets: An Examination of the Codex Standard and Country-Specific Differences in Gluten-Free-Food Labeling Regulations, for Oats and Oats Declared as Ingredients in Gluten-Free Products.

Nutrition reviews·2026
Same journal

Ultra-Processed Foods and Health Outcomes in Children and Adults: An Updated Narrative Umbrella Review With a Focus on Dose-Response.

Nutrition reviews·2026
Same journal

A Scoping Review of Nutritional Guidelines and Practices in Day Care Centers.

Nutrition reviews·2026
Same journal

Time-Restricted Feeding/Eating and Muscle Aging: Research Progress from Molecular Mechanisms to Personalized Intervention Strategies.

Nutrition reviews·2026
See all related articles

Area of Science:

  • Pharmacology
  • Nutritional Science
  • Geriatric Medicine

Background:

  • Nutrition status significantly impacts drug pharmacodynamics and therapeutic efficacy.
  • Disease states and special conditions can alter nutrient status.
  • Drug efficacy can be compromised by interactions with food and nutrient deficiencies.

Purpose of the Study:

  • To explore the relationship between nutrition status and drug pharmacodynamics.
  • To examine how disease states and special conditions affect nutrient status and drug efficacy.
  • To highlight the impact of food and nutrient interactions on drug therapy, particularly in geriatric patients.

Main Methods:

  • Literature review on nutrition-drug interactions.
  • Analysis of pharmacokinetic and pharmacodynamic data.

Related Experiment Videos

  • Case studies on special populations, including geriatric patients.

    • Main Results:

    • Many drug classes, including antimicrobials, hypoglycemics, and hypocholesterolemic agents, are affected by food.
    • Nutrients and pathophysiologic conditions like aging and hepatic dysfunction can modify drug pharmacokinetic profiles.
    • Geriatric patients are particularly vulnerable to nutrition-related drug efficacy alterations.

    Conclusions:

    • Nutrition status is a critical determinant of drug response.
    • Understanding nutrient-drug interactions is essential for optimizing therapeutic outcomes.
    • Special attention to nutrition is required in drug therapy for vulnerable populations, especially the elderly.