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[Bis-(hydroxy-2-ethylthyo)-1,10-decano in hyperlipaemic therapy (author's transl)]
Giornale Italiano Di Cardiologia
|January 1, 1977
Summary
Tiadenol effectively lowers cholesterol and triglycerides in hyperlipaemic patients, matching clofibrate
Area of Science:
- Pharmacology and Therapeutics
- Cardiovascular Medicine
Background:
- Hyperlipidemia is a significant risk factor for atherosclerotic disease.
- Current treatments like clofibrate aim to manage lipid levels.
Purpose of the Study:
- To evaluate the efficacy and biological tolerability of Tiadenol.
- To compare Tiadenol's lipid-lowering effects with clofibrate.
Main Methods:
- A study involving 38 hyperlipaemic volunteers (with or without atherosclerosis).
- Comparative analysis of Tiadenol and clofibrate treatments.
Main Results:
- Tiadenol demonstrated significant reductions in cholesterolemia and trigliceridaemia.
- The hypolipidemic effect of Tiadenol was comparable to clofibrate.
- Statistical examination confirmed the observed results.
Conclusions:
- Tiadenol is an effective hypolipidemic agent.
- Tiadenol exhibits excellent biological tolerability with no observed side-effects.