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Related Experiment Videos

[Oral hormonal contraception: more or less estrogens?]

B Rubio Lotvin1

  • 1Facultad de Medicina, Universidad Nacional Autónoma de México.

Ginecologia Y Obstetricia De Mexico
|December 1, 1995
PubMed
Summary

Desogestrel and ethinylestradiol oral contraceptives offer flexible dosing options for various women. The choice between 20 mcg and 30 mcg ethinylestradiol depends on individual user characteristics and health considerations.

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Area of Science:

  • Reproductive Endocrinology
  • Contraception
  • Pharmacology

Context:

  • Oral contraceptives (OCs) containing desogestrel and varying doses of ethinylestradiol are widely used.
  • Individual patient factors significantly influence the selection of appropriate OC formulations.

Purpose:

  • To outline practical guidelines for selecting between 20 mcg and 30 mcg ethinylestradiol/desogestrel formulations.
  • To provide a user-centered approach to oral contraceptive prescription based on clinical experience.

Summary:

  • The 20 mcg ethinylestradiol dose is recommended for adolescents without acne, users under 60 kg, those with heavy bleeding or large breasts, post-ideal weight obese patients, and women over 35 or perimenopausal/postmenopausal.
  • The 30 mcg ethinylestradiol dose is suggested for adolescents with acne, those with scanty bleeding or small breasts, users over 60 kg, and obese patients currently undergoing weight reduction.

Impact:

  • Facilitates personalized oral contraceptive selection, potentially improving efficacy and user satisfaction.
  • Offers a clinical framework for optimizing desogestrel-containing contraceptive use in diverse patient populations.

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