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Effective treatment of drug-induced agranulocytosis using recombinant human granulocyte colony stimulating factor in
1Department of Obstetrics and Gynecology, Simane Medical University, Izumo, Japan.
Gynecologic and Obstetric Investigation
|January 1, 1995
Abstract:
Drug-induced immune system mediated agranulocytosis is a rare but potentially life-threatening condition. There have been only a few reports on the drug-induced agranulocytosis during pregnancy. We present a case of agranulocytosis after prolonged intravenous infusion of ritodrine hydrochloride and additional administration of indomethacin suppositories, effectively treated using recombinant human granulocyte colony stimulating factor without any infection in a mother with twin-to-twin transfusion syndrome. Recombinant human granulocyte colony stimulating factor may have a potential use for drug-induced agranulocytosis during pregnancy.