Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pustular psoriasis precipitated by acetazolamide

K Kuroda1, T Kojima, E Tanabe

  • 1Department of Dermatology, School of Medicine, Chiba University, Japan.

The Journal of Dermatology
|October 1, 1995
PubMed
Summary

Acetazolamide, a carbonic anhydrase inhibitor, can trigger pustular psoriasis flare-ups. This case highlights the drug

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026
Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025
Same author

Constraints on Cosmic Strings Using Data from the Third Advanced LIGO-Virgo Observing Run.

Physical review letters·2021
Same author

Oxaliplatin-based adjuvant chemotherapy duration (3 versus 6 months) for high-risk stage II colon cancer: the randomized phase III ACHIEVE-2 trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2020
Same author

Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA.

Living reviews in relativity·2020
Same author

Reactive increase in gastric mucus secretion is an adaptive defense mechanism against low-dose aspirin-induced gastropathy.

Digestive diseases and sciences·2013

Area of Science:

  • Dermatology
  • Ophthalmology
  • Pharmacology

Background:

  • Generalized pustular psoriasis is a severe skin condition.
  • Glaucoma treatment often involves carbonic anhydrase inhibitors.
  • Psoriatic arthritis can coexist with skin manifestations.

Observation:

  • A 28-year-old man with generalized pustular psoriasis developed glaucoma.
  • Acetazolamide was initiated for glaucoma treatment.
  • The patient experienced a severe exacerbation of pustular lesions and erythema.

Findings:

  • Acetazolamide precipitated generalized pustular psoriasis and widespread erythema.
  • Discontinuation of acetazolamide and treatment with etretinate led to improvement.
  • Re-administration of acetazolamide rapidly triggered pustule formation, confirming causality.

Implications:

  • Clinicians should be aware of acetazolamide's potential to induce or worsen pustular psoriasis.
  • Careful patient selection and monitoring are crucial when prescribing acetazolamide to individuals with psoriasis.
  • This case underscores the importance of considering drug-induced exacerbations in dermatological conditions.

Related Experiment Videos