Alcohol intake and cardiovascular mortality in hypertensive patients: report from the Department of Health

A J Palmer1, A E Fletcher, C J Bulpitt

  • 1Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.

Journal of Hypertension
|September 1, 1995
PubMed

Insights

Moderate alcohol consumption may reduce stroke and heart disease mortality in treated hypertensives. However, higher intakes increase non-circulatory mortality, with 1-10 units weekly showing lowest overall risk in men.

Area of Science:

  • Cardiovascular Medicine
  • Public Health
  • Epidemiology

Background:

  • Hypertension management often involves lifestyle modifications, including alcohol consumption.
  • The impact of alcohol on cardiovascular outcomes in treated hypertensive patients requires further clarification.

Purpose of the Study:

  • To investigate the association between alcohol intake and mortality from ischemic heart disease, stroke, and all causes in treated hypertensive individuals.

Main Methods:

  • Prospective study of 6,369 treated hypertensive patients in the UK.
  • Relative risks for mortality were calculated comparing drinkers to non-drinkers and by level of alcohol consumption.
  • Adjustments were made for confounding factors like age, smoking, and prior cardiovascular disease.

Main Results:

  • Alcohol consumption was common in treated hypertensives (76% men, 48% women).
  • Male drinkers showed reduced stroke mortality risk and potential reduction in ischemic heart disease mortality.
  • Non-drinkers were older, less likely to smoke, and had higher untreated blood pressure.

Conclusions:

  • Alcohol intake, particularly 1-10 units per week, may be associated with lower overall mortality in treated hypertensive men.
  • While alcohol may reduce cardiovascular mortality, higher consumption increases non-circulatory mortality risks.
  • Findings suggest a potential benefit for stroke mortality reduction in treated hypertensives with moderate alcohol intake.
Abstract

Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...