Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Toxoplasma IgG. & IgM. antibodies. A case control study

R A Attia1, M M el-Zayat, H Rizk

  • 1Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.

Journal of the Egyptian Society of Parasitology
|December 1, 1995
PubMed
Summary

Toxoplasma infection is linked to spontaneous abortions. Higher levels of Toxoplasma IgG and IgM antibodies were found in women experiencing miscarriages compared to controls, indicating a significant association.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protective effect of resveratrol on acrylamide-induced renal impairment.

Folia morphologica·2020
Same author

Concomitant administration of sitagliptin and rutin improves the adverse hepatic alterations in streptozotocin-induced diabetes mellitus in albino rats: an overview of the role of alpha smooth muscle actin.

Folia morphologica·2020
Same author

Foreign body inhalation in the pediatric population: lessons learned from 106 cases.

European annals of otorhinolaryngology, head and neck diseases·2011
Same author

Coccidiosis among malnourished children in Mansoura, Dakahlia Governorate, Egypt.

Journal of the Egyptian Society of Parasitology·2002
Same author

Rapid detection of a Schistosoma mansoni circulating antigen excreted in urine of infected individuals by using a monoclonal antibody.

Journal of clinical microbiology·1999
Same author

Fast-Dot ELISA using urine, a rapid and dependable field assay for diagnosis of schistosomiasis.

Journal of the Egyptian Society of Parasitology·1997

Area of Science:

  • Medical Parasitology
  • Immunology
  • Reproductive Health

Background:

  • Toxoplasma gondii is a protozoan parasite with a global distribution.
  • Infection during pregnancy can lead to adverse outcomes, including spontaneous abortion.
  • Understanding the seroprevalence and impact of Toxoplasma infection in women with a history of abortion is crucial for public health.

Purpose of the Study:

  • To investigate the association between Toxoplasma gondii infection and spontaneous abortions.
  • To compare the levels of Toxoplasma-specific IgM and IgG antibodies in women with spontaneous abortions versus controls.
  • To identify risk factors associated with Toxoplasma infection in aborting women.

Main Methods:

  • A case-control study involving 62 women with spontaneous abortions and 75 non-pregnant multiparous controls.

Related Experiment Videos

  • Micro-ELISA was employed to quantify Toxoplasma gondii IgM and IgG antibodies in serum samples.
  • Statistical analysis was performed to compare antibody levels and identify significant differences.

    • Main Results:

    • A significant difference in Toxoplasma IgG and IgM antibody levels was observed between women with spontaneous abortions and controls.
    • Elevated IgG antibody levels were significantly associated with a history of three or more abortions.
    • Higher infection rates were noted in rural areas, linked to poor hygiene and lack of awareness.

    Conclusions:

    • Toxoplasma infection is significantly associated with spontaneous abortions.
    • Serological evidence of Toxoplasma infection is more prevalent in women experiencing recurrent miscarriages.
    • Public health initiatives focusing on hygiene and awareness are needed, especially in rural populations.