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Renal sonographic patterns in Bartter's syndrome

S A Al-Rasheed1, P J Patel, T M Kolawole

  • 1Pediatric Department (39) and Department of Radiology, King Khalid University Hospital, P. O. Box 2925, Riyadh 11461, Saudi Arabia.

Pediatric Radiology
|January 1, 1996
PubMed
Summary
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Renal ultrasound in Bartter syndrome reveals varied abnormalities beyond hyperechoic pyramids. Early suspicion is aided by nephrocalcinosis in children with polyhydramnios and premature delivery history.

Area of Science:

  • Nephrology
  • Radiology
  • Pediatrics

Background:

  • Bartter syndrome is a rare genetic disorder affecting kidney salt reabsorption.
  • Previous studies primarily described hyperechoic renal pyramids in Bartter syndrome.
  • Accurate diagnosis relies on identifying characteristic clinical and imaging findings.

Purpose of the Study:

  • To describe the spectrum of renal sonographic findings in Bartter syndrome.
  • To identify potential sonographic markers beyond previously reported abnormalities.
  • To assess the utility of ultrasound in early Bartter syndrome detection.

Main Methods:

  • Retrospective analysis of renal sonographic data from ten patients with Bartter syndrome.
  • Detailed examination of renal echogenicity, including pyramids and surrounding parenchyma.

Related Experiment Videos

  • Correlation of sonographic findings with clinical history, including polyhydramnios and premature delivery.

    • Main Results:

    • Observed sonographic abnormalities included diffuse increased renal echogenicity.
    • Hyperechoic echogenicity was noted throughout the kidneys, sparing the pyramids.
    • Nephrocalcinosis was identified as a significant associated finding.

    Conclusions:

    • Renal sonography in Bartter syndrome can present with diverse abnormalities, not limited to hyperechoic pyramids.
    • Diffuse increased renal echogenicity and nephrocalcinosis are important sonographic indicators.
    • Suspecting Bartter syndrome early is possible with nephrocalcinosis in infants with polyhydramnios and premature delivery.