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Methods for the transcervical collection of fetal cells during the first trimester of pregnancy
C Rodeck1, B Tutschek, J Sherlock
1Department of Obstetrics and Gynaecology, University College London, U.K.
Prenatal Diagnosis
|October 1, 1995
Abstract:
Before termination of pregnancy, four techniques for retrieving fetal cells transcervically were investigated: uterine lavage, endocervical lavage, cytobrush and mucus aspiration. The yield of fetal cells in these samples was studied and found to be somewhat better after uterine lavage. A preliminary assessment of the safety of mucus aspiration was carried out before transcervical chorionic villus sampling (CVS) in continuing pregnancies. No difference in outcome to a control group having only CVS was found.