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Updated: Aug 27, 2026

A Semi-automated Approach to Preparing Antibody Cocktails for Immunophenotypic Analysis of Human Peripheral Blood
Published on: February 8, 2016
An automated hematology laboratory with computer-controlled robotics
L W Diamond1, D T Nguyen, B L Sheridan
1Pathology Institute, University of Cologne, Joseph-Stelzmann Strasse 9, 50924, Cologne, Germany.
Abstract:
A highly automated hematology laboratory environment is described that has conveyance systems to move bar-coded specimens from one station ("workcell") to another, robotic handling devices to load and unload hematology analyzers, and a hematology workstation. Computer systems monitor the process and equipment, track the specimen, manage inventory, and interpret patient results. When a specimen arrives at the laboratory, the bar-code determines which workcell the specimen should go to for testing. Each specimen is handled individually and in real-time. Hematology specimens are routed to a workcell of Coulter STKS analyzers where complete blood counts with five-part leukocyte differentials are performed under full robotic control. The entire process is managed by a real-time Windows-based process control system that interacts with a networked laboratory information system. The hematology workstation is being evaluated for interpretive results reporting and to determine follow-up testing.

