Branchiogenic carcinoma--a case for radiation induced carcinogenesis

From the time the first case of bronchial cleft carcinoma was reported over a century ago, very few cases have been reported which prove to be a cancer of primary branchial origin, while many metastatic cystic squamous cell carcinomas in the neck have been wrongly categorized as branchial carcinoma. Here, we describe a case of primary branchiogenic carcinoma in a 53 year old Libyan female showing a transformation of a benign epithelium into a malignant type. We further report that this transformation is perhaps brought about by an irregular radiotherapy to the head and neck region.