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Activity of sucralfate (sucrose octa-sulphate), an anti-ulcer agent, against opportunistic gram-negative bacilli
S G Bragman1, C L Pankhurst, M W Casewell
1Dulwich Public Health Laboratory, King's College School of Medicine and Dentistry, London, UK.
The Journal of Antimicrobial Chemotherapy
|October 1, 1995
Abstract:
The in-vitro activity of sucralfate (sucrose octa-sulphate) in suspension was examined against 128 strains of Gram-negative bacilli. Inhibitory activity was demonstrated against all isolates and bactericidal activity was demonstrated for 68. Sucralfate has inhibitory and bactericidal antibacterial activity which may contribute to its in-vivo clinical efficacy.