Histopathology of childhood renal tumors

The different subtypes of childhood renal tumors are well defined both clinically and pathologically. Classification and estimation of prognosis are feasible even after chemotherapy. A small group of tumors remains in which an estimate of prognosis is difficult. This is especially true for Wilms tumors with persistent blastema after chemotherapy. It is to be hoped that studies of the molecular genetics of these tumors will yield new data that will help refine therapeutic strategies.