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Pustular psoriasis of pregnancy
S H Lee1, M J Hunt, R S Barnetson
1Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
The Australasian Journal of Dermatology
|November 1, 1995
Summary
Generalized pustular psoriasis of pregnancy is a rare condition. This case report details successful treatment with oral steroids after topical therapies failed.
Area of Science:
- Dermatology
- Obstetrics
- Immunology
Background:
- Generalized pustular psoriasis (GPP) is a severe dermatosis.
- Pregnancy can trigger or exacerbate various skin conditions.
- Pustular psoriasis of pregnancy (PPP) is a rare variant of GPP.
Observation:
- An 18-year-old woman presented with GPP in her first pregnancy at 23 weeks gestation.
- Initial treatment with topical therapies provided no relief.
- The patient's condition worsened despite conservative management.
Findings:
- Systemic corticosteroid therapy was initiated.
- Rapid and significant improvement in skin lesions was observed following oral steroid administration.
- This suggests a crucial role for systemic anti-inflammatory treatment in managing PPP.
Implications:
- Early recognition and prompt systemic treatment are vital for managing GPP in pregnancy.
- Oral corticosteroids appear to be an effective therapeutic option for PPP.
- Further research is warranted to explore optimal management strategies and long-term outcomes for PPP.