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Benzyl alcohol allergy

M Li1, E Gow

  • 1Skin and Cancer Foundation, Westmead, New South Wales, Australia.

The Australasian Journal of Dermatology
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

A patient with persistent vulval lichen sclerosus et atrophicus and dermatitis was found to be allergic to benzyl alcohol. This common preservative in topical treatments may cause or worsen these vulval conditions.

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Area of Science:

  • Dermatology
  • Allergology
  • Vulval Dermatology

Background:

  • Lichen sclerosus et atrophicus (LS&A) and dermatitis are chronic inflammatory vulval conditions.
  • Refractory cases often necessitate investigation into contact allergies.
  • Topical therapies are standard but can sometimes induce or exacerbate symptoms.

Observation:

  • A 63-year-old woman presented with a 3-year history of treatment-resistant vulval LS&A and dermatitis.
  • Standard topical treatments had proven ineffective.
  • Patch testing was performed to identify potential allergens.

Findings:

  • The patient exhibited a positive patch test reaction to 5% benzyl alcohol.
  • Benzyl alcohol is a common preservative found in many topical pharmaceutical preparations.

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  • It is also a constituent of balsam of Peru, a known contact allergen.

    • Implications:

    • Benzyl alcohol allergy should be considered in patients with recalcitrant vulval LS&A and dermatitis.
    • Identifying and avoiding this allergen can lead to improved treatment outcomes.
    • This highlights the importance of comprehensive patch testing in complex vulval dermatoses.