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[Primary amyloidosis of bones. MRI aspects]
C Faure1, B Venin, J C Bousquet
1Service de Radiologie Ostéo-Articulaire et Neuro-Radiologie, Hôpital Edouard-Herriot, Lyon.
Journal De Radiologie
|November 1, 1995
Summary
Primary systemic amyloidosis can cause vertebral collapse. Magnetic resonance imaging (MRI) aids in diagnosing vertebral amyloidosis, especially in non-traumatic fractures.
Area of Science:
- Radiology
- Oncology
- Hematology
Background:
- Primary systemic amyloidosis is a rare plasma cell disorder.
- Vertebral collapse is an uncommon manifestation of systemic amyloidosis.
Observation:
- A patient presented with multiple vertebral fractures.
- Magnetic resonance imaging (MRI) revealed diffuse bone marrow abnormalities.
- Characteristic low signals in vertebral bodies on T1 and T2 weighted images were noted.
Findings:
- Bone biopsy confirmed vertebral amyloid deposition.
- MRI effectively demonstrated the extent of bone marrow involvement.
Implications:
- MRI is valuable for assessing the spread of amyloidosis in bones.
- This imaging technique can aid in diagnosing amyloidosis presenting with vertebral fractures.