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Database on the structure of large ribosomal subunit RNA
P De Rijk1, Y Van de Peer, R De Wachter
1Departement Biochemie, Universiteit Antwerpen (UIA), Belgium.
Nucleic Acids Research
|January 1, 1996
Summary
A database of 334 large ribosomal subunit RNA sequences, aligned with secondary structure, is now available. This valuable resource for molecular biology research can be accessed online.
Area of Science:
- Molecular Biology
- Bioinformatics
- Genomics
Background:
- Ribosomal RNA (rRNA) is crucial for protein synthesis.
- Large ribosomal subunit rRNA sequences are important for phylogenetic and functional studies.
- A centralized, curated database of aligned rRNA sequences with secondary structure is needed.
Purpose of the Study:
- To present a comprehensive database of large ribosomal subunit RNA sequences.
- To provide aligned sequences incorporating secondary structure information.
- To make these data easily accessible to the research community.
Main Methods:
- Compilation of 334 large ribosomal subunit RNA sequences as of July 1995.
- Alignment of all sequences considering secondary structure.
- Data provision in multiple computer-readable formats.
Main Results:
- A database containing 334 aligned large ribosomal subunit RNA sequences with secondary structure information.
- Data available in various formats for computational analysis.
- Easy accessibility via World Wide Web and anonymous FTP.
Conclusions:
- The database serves as a valuable resource for researchers studying ribosomal RNA.
- Facilitates comparative analysis and structural studies of large ribosomal subunits.
- Promotes accessibility and utilization of rRNA sequence data in molecular biology.