Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Separating local from global effects in neural pair correlograms

J J Eggermont1, G M Smith

  • 1Department of Psychology, University of Calgary, Alberta, Canada.

Neuroreport
|November 13, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low doses of ionising radiation: definitions and contexts.

Journal of radiological protection : official journal of the Society for Radiological Protection·2024
Same author

Further development and application of a method for assessing radionuclide surface activity distribution and source location based on measurements of ambient dose equivalent rate.

Journal of radiological protection : official journal of the Society for Radiological Protection·2023
Same author

Further development and application of a method for assessing radionuclide surface activity distribution and source location based on measurements of ambient dose equivalent rate. Examples for Andreeva Bay, Chernobyl NPP and Istiklol.

Journal of radiological protection : official journal of the Society for Radiological Protection·2023
Same author

Progress with the regulation of radiation safety during recovery and removal of spent nuclear fuel from the site for temporary storage at Andreeva Bay on the Kola Peninsula.

Journal of radiological protection : official journal of the Society for Radiological Protection·2023
Same author

A research and development roadmap to support applications of the enhanced BIOMASS methodology.

Journal of radiological protection : official journal of the Society for Radiological Protection·2022
Same author

Topographical classification of dose distributions: implications for control for worker exposure.

Journal of radiological protection : official journal of the Society for Radiological Protection·2020
Same journal

Electroacupuncture alleviates neuroinflammation and promotes recovery of neurological functions after intracerebral hemorrhage by modulating α7nAChR/JAK2/STAT3 signaling pathway.

Neuroreport·2026
Same journal

Non-cell-autonomous regulation of Bhlhb5 expression in cortical projection neurons by GABAergic interneuron development and position.

Neuroreport·2026
Same journal

C-C motif chemokine ligand 3 mediates inflammatory response via NLRP3 inflammasome and neuron damage after traumatic brain injury.

Neuroreport·2026
Same journal

Methyltransferase-like 14 alleviates neuronal ferroptosis in Alzheimer's disease by regulating the peroxiredoxin 6/apoptosis signal-regulating kinase 1 signaling pathway.

Neuroreport·2026
Same journal

Hand mental rotation reaction time reflects motor imagery strategy and predicts changes in finger dexterity after motor imagery.

Neuroreport·2026
Same journal

Functional exploration of metabotropic glycine receptors in cultured rat hippocampal slices.

Neuroreport·2026
See all related articles

This study introduces a method to estimate global synchronization effects on neural firing patterns using local field potentials (LFPs). This helps reveal local connectivity masked by widespread brain activity.

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Systems Neuroscience

Background:

  • Cross-correlograms of simultaneously recorded neural spike trains reveal synchronization patterns.
  • Peak widths in cross-correlograms reflect both local connectivity and global synchronization forces.
  • Strong global synchrony can obscure the contribution of local neuronal connections.

Purpose of the Study:

  • To develop an estimator for quantifying global synchronizing effects on unit-pair correlations.
  • To differentiate global synchrony from local connectivity influences in neural recordings.
  • To investigate the conditions under which global synchronization is most prominent.

Main Methods:

  • Utilized cross-correlograms of simultaneously recorded neuronal spike trains.

Related Experiment Videos

  • Employed local field potentials (LFPs) as a measure of global synchronizing activity.
  • Developed a novel estimator based on LFP data to predict global effects on spike train correlations.

    • Main Results:

    • The proposed LFP-based estimator effectively predicts global synchronizing effects on unit-pair correlations.
    • Global synchronizing influences are most significant during spontaneous neural activity.
    • The impact of global synchronization is more pronounced for neurons recorded from distant electrodes.

    Conclusions:

    • Local field potentials can serve as a valuable tool to estimate global synchronization in neural networks.
    • Distinguishing global from local influences is crucial for understanding neural circuit function.
    • The findings highlight the importance of considering global network states when analyzing local neuronal interactions.