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Lipopolysaccharide activates the sea urchin immune system
L C Smith1, R J Britten, E H Davidson
1Division of Biology, California Institute of Technology, Pasadena 91125, USA.
Developmental and Comparative Immunology
|May 1, 1995
Abstract:
Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocytes activation in response to injury. Here we show that coelomocytes respond to immune challenge from lipopolysaccharide with significant elevations in profilin transcripts per coelomyocyte.