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Published on: August 25, 2015
Gastroesophageal reflux. Diagnostic and therapeutic approaches
1Division of Pediatric Gastroenterology, University of Michigan, Ann Arbor, Michigan 48109-0200, USA.
Insights
Diagnosing gastroesophageal reflux in infants can be challenging, especially with subtle symptoms. This review clarifies diagnostic approaches to avoid unnecessary tests for healthy infants.
Area of Science:
- Pediatric Gastroenterology
- Infant Health
Background:
- Gastroesophageal reflux is common in infants.
- Distinguishing between physiologic and pathologic reflux is clinically significant.
- Over-investigation of healthy infants is a concern.
Purpose of the Study:
- To review the physiology of gastroesophageal reflux in infants.
- To outline clinical presentations and diagnostic strategies.
- To discuss therapeutic options for infant gastroesophageal reflux.
Main Methods:
- Literature review on infant gastroesophageal reflux.
- Synthesis of information on diagnosis and management.
- Focus on differentiating reflux types and appropriate testing.
Main Results:
- Clear guidelines for diagnosing gastroesophageal reflux are needed.
- Subtle signs require careful evaluation to identify pathologic conditions.
- Appropriate diagnostic tests are crucial to avoid invasive procedures.
Conclusions:
- Accurate diagnosis of infant gastroesophageal reflux is essential.
- Understanding reflux physiology aids clinical decision-making.
- Judicious use of diagnostic tests prevents unnecessary infant interventions.
Abstract:
The clinical challenge of determining the medical conditions that are associated with obvious symptoms of gastroesophageal reflux and what diagnostic tests are appropriate to define this relationship is substantial. To determine which infants may be suffering from pathologic conditions associated with subtle signs of gastroesophageal reflux is even more challenging. This determination is essential to avoid subjecting many healthy infants to costly and potentially invasive testing. This article focuses on the physiology, clinical presentations, diagnosis and evaluation, and therapy of gastroesophageal reflux.
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