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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Outcome of percutaneous intervention in iliac artery stents
M R Sapoval1, A L Long, J Y Pagny
1Department of Cardiovascular Radiology, Inserm U-256, Hôpital Broussais, Paris, France.
Insights
Secondary procedures in iliac artery stents are safe and effective for treating restenosis and occlusion. While successful, ongoing monitoring is crucial as stenosis can recur over time.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Medical Device Technology
Background:
- Iliac artery stents are used to treat peripheral artery disease.
- Restenosis and occlusion are common complications following stent placement.
- Secondary interventions are sometimes necessary to maintain stent patency.
Purpose of the Study:
- To evaluate the safety and effectiveness of repeat interventional procedures for iliac artery stents.
- To assess outcomes in patients requiring secondary procedures for restenosis or occlusion.
Main Methods:
- Retrospective analysis of 34 patients (36 limbs) undergoing secondary procedures.
- Procedures targeted restenosis (30 limbs) or occlusion (6 limbs).
- Clinical and angiographic follow-up, including duplex ultrasound, assessed primary and secondary patency.
Main Results:
- 100% immediate angiographic success with 4 complications.
- Primary patency rates at 6 months, 1 year, and 2 years were 77.5%, 73%, and 51.4% respectively.
- Secondary patency rates at 6 months, 1 year, and 2 years were 94%, 89.3%, and 78.8% respectively, with 80% nominal patency at study end (20.1 months).
Conclusions:
- Percutaneous interventions are effective for treating restenosis and chronic occlusion in iliac artery stents.
- While secondary procedures yield good results, the potential for recurrent stenosis exists.
- Long-term patency can be achieved, but continued surveillance is warranted.
Purpose:
To assess the safety and efficacy of secondary procedures in iliac artery stents.
Materials And Methods:
Thirty-four patients (36 limbs) underwent one or more interventional procedures in iliac artery stents to treat restenosis (n = 30) or occlusion (n = 6). All patients were followed up by means of clinical and angiographic examination. Primary and secondary patency were assessed with angiography, duplex ultrasound, or both. Primary patency was determined after one interventional procedure, and secondary patency was determined at the end of the study (mean +/- standard deviation, 20.1 months +/- 17.5; range, 1-58 months).
Results:
Immediate angiographic success was achieved in all cases. Four complications were observed. The primary and secondary cumulative patency rates were 77.5% +/- 7.6 and 94% +/- 4.1 at 6 months, 73% +/- 8.4 and 89.3% +/- 6 at 12 months, and 51.4% +/- 10.9 and 78.8% +/- 8.8 at 2 years. At the end of the study, 80% of the arteries were still nominally patent.
Conclusion:
Restenosis and chronic occlusion in iliac artery stents can be treated with percutaneous interventional procedures; however, stenosis can still recur.
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