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Related Experiment Videos

A precise and fast temperature mapping using water proton chemical shift

Y Ishihara1, A Calderon, H Watanabe

  • 1Toshiba R & D Center, Kawasaki, Japan.

Magnetic Resonance in Medicine
|December 1, 1995
PubMed
Summary

This study introduces a novel phase mapping technique for precise temperature measurement using water proton chemical shift. The method achieves rapid, accurate temperature readings in phantoms and in vivo, crucial for biological research.

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Area of Science:

  • Magnetic Resonance Imaging
  • Biomedical Engineering
  • Thermodynamics

Background:

  • Accurate temperature monitoring is vital for understanding biological processes and ensuring safety in medical treatments.
  • Existing temperature measurement methods can be slow, invasive, or lack sufficient spatial resolution.

Purpose of the Study:

  • To develop and validate a new non-invasive temperature measurement procedure utilizing the temperature dependence of water proton chemical shift.
  • To assess the accuracy and speed of this technique in both phantom and in vivo settings.

Main Methods:

  • Phase mapping technique based on the temperature-dependent water proton chemical shift.
  • Utilized a field echo pulse sequence (TR/TE = 115/13 ms, matrix = 128 x 128, 5 slices) for phantom experiments.

Related Experiment Videos

  • Applied the method to measure temperature changes in a cat's brain.

    • Main Results:

    • Achieved accuracy > +/- 0.5°C within seconds per slice in water phantoms.
    • Demonstrated consistent temperature dependence of water proton chemical shift across tissue-similar materials (water, glucide, protein).
    • Obtained in vivo temperature changes in a cat's brain with > +/- 1°C accuracy and 0.6 x 0.6 mm in-plane resolution.

    Conclusions:

    • The developed phase mapping method offers a fast and accurate approach for temperature measurement.
    • In vivo measurements are influenced by factors like B0 shifts and blood flow, with position shifts being most significant.
    • This technique holds promise for real-time temperature monitoring in biological systems.