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Related Experiment Videos

A simple quality control protocol for haemoximetry using standard p50

J Morgan1, A Clague, J Rayfield

  • 1Royal Brisbane Hospital, Queensland, Australia.

Acta Anaesthesiologica Scandinavica. Supplementum
|January 1, 1995
PubMed
Summary

This study introduces a novel quality control tool for haemoximetry. The method detects inaccuracies in blood gas analyzers by monitoring standard p50 values during progressive oxygenation, ensuring reliable extractivity parameter measurements.

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Area of Science:

  • Clinical Chemistry
  • Biomedical Engineering
  • Medical Diagnostics

Background:

  • Accurate haemoximetry is crucial for determining blood oxygen parameters.
  • Existing quality control methods may not detect subtle haemoximetry inaccuracies.
  • Errors in haemoximetry can lead to significant errors in derived extractivity parameters.

Purpose of the Study:

  • To develop a quality control tool for haemoximetry.
  • To identify inaccuracies in blood gas analyzers that affect extractivity parameters.
  • To provide an easy-to-perform protocol for ensuring haemoximetry accuracy.

Main Methods:

  • Utilizing the Siggaard-Andersen algorithm to calculate standard p50 from blood gas and haemoximetry measurements.
  • Assessing the constancy of standard p50 as a venous blood specimen is progressively oxygenated to 97% haemoglobin saturation.

Related Experiment Videos

  • Detecting deviations in standard p50 above 80% saturation as an indicator of haemoximeter inaccuracy.

    • Main Results:

    • The designed tool effectively detects haemoximeter inaccuracies.
    • Deviations in standard p50 become progressively larger above 80% saturation in inaccurate devices.
    • The method identifies errors undetectable by standard quality control materials using non-haemoglobin dyes.

    Conclusions:

    • The proposed quality control protocol is easy to implement.
    • This method enhances the reliability of blood gas analyser/haemoximeter performance.
    • It is recommended for quality control, particularly for determining arterial extractivity parameters.