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Pulp reaction to a dentin bonding agent

C H Pameijer¹, H R Stanley

¹University of Connecticut, School of Dental Medicine, Department of Prosthodontics, Farmington, CT 06030, USA.

American Journal of Dentistry

|June 1, 1995

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Prisma Universal Bond 2 (PUB-2) demonstrated favorable pulpal biocompatibility in monkey teeth. Histological evaluation revealed only mild, transient inflammatory responses, indicating its safety for dental applications.

Area of Science:

Biomaterials Science
Dental Materials
Histology

Background:

Assessing the biocompatibility of dental materials is crucial for predicting clinical outcomes.
Prisma Universal Bond 2 (PUB-2) is a dental adhesive system requiring evaluation for pulpal interaction.

Purpose of the Study:

To evaluate the pulpal biocompatibility of Prisma Universal Bond 2 (PUB-2) in a preclinical model.

Main Methods:

Class V cavities were prepared in subhuman primate teeth, approximating the pulp.
Teeth were restored using PUB-2 with or without a liner, or with control materials (IRM, silicate cement).
Histological analysis was performed at 5, 25, and 60 days post-application.

Main Results:

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Prisma Universal Bond 2 (PUB-2) exhibited a mild inflammatory response at 5 days, which resolved by 25 and 60 days.

The observed reactions were comparable to the negative control (IRM).

Conclusions:

Prisma Universal Bond 2 (PUB-2) demonstrates acceptable pulpal biocompatibility.
The material is suitable for use in direct or indirect pulp capping scenarios.