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Arsenic in Dermatology

M E Maloney1

  • 1Division of Dermatology, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, 17033, USA.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|March 1, 1996
PubMed
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Arsenic exposure, a known carcinogen, poses risks for skin and internal cancers. Public awareness and regular medical screenings are crucial for individuals with known arsenic exposure.

Area of Science:

  • Environmental Health
  • Toxicology
  • Dermatology

Background:

  • Arsenic is a naturally occurring and occupational chemical carcinogen.
  • Exposure can occur through environmental or workplace sources.

Purpose of the Study:

  • To review arsenic exposure pathways.
  • To outline clinical signs associated with arsenic exposure.
  • To assess the carcinogenic potential of arsenic.

Main Methods:

  • A comprehensive literature review was conducted.
  • Existing research on arsenic toxicology and clinical manifestations was analyzed.

Main Results:

  • Arsenic is a confirmed human carcinogen.
  • Exposure is linked to cutaneous malignancies, hyperpigmentation, and palmar/plantar keratosis.

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  • Internal malignancies, particularly lung and bladder cancers, are associated with arsenic exposure.

    • Conclusions:

    • Public awareness campaigns regarding arsenic exposure risks are essential.
    • Individuals with documented arsenic exposure require regular dermatological examinations.
    • Close medical follow-up by primary care physicians is recommended for those with known exposure.