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[Colonic ulcer in HIV (+) patients]
C Varsky1, C Martínez López, A Dutack
1Servicio de Endoscopía, Hospital Nacional Profesor Alejandro Posadas, Haedo, Argentina.
Acta Gastroenterologica Latinoamericana
|January 1, 1995
Summary
Rectocolonic ulcers in HIV patients were investigated. Cytomegalovirus was a common cause, but many idiopathic lesions were also found, particularly in homosexual men.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Oncology
Context:
- Rectocolonic ulcers are a significant endoscopic finding in patients with Human Immunodeficiency Virus (HIV).
- Understanding the etiology of these ulcers is crucial for diagnosis and management in immunocompromised individuals.
Purpose:
- To investigate the causes of rectocolonic ulcers in a cohort of HIV-positive patients undergoing endoscopic procedures.
- To identify common pathogens and conditions associated with these ulcers.
Summary:
- A study of 28 colonoscopies and 12 rectoscopies in HIV patients revealed 18 cases of rectocolonic ulcers.
- Cytomegalovirus (CMV) was diagnosed in 6 patients, with intestinal tuberculosis, rectal herpes (HSV type 1), and Burkitt's lymphoma identified in others.
- Notably, 9 patients had idiopathic lesions, and a higher prevalence was observed in male homosexuals.
Impact:
- Highlights the diverse range of etiologies for rectocolonic ulcers in HIV patients, including opportunistic infections and idiopathic causes.
- Suggests that hematochezia is a frequent symptom associated with these ulcers.
- Emphasizes the need for thorough investigation, as some ulcers may indicate advanced HIV/AIDS or malignancy.