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Fluorescein angiography in nonischemic optic disc edema
A C Arnold1, M A Badr, R S Hepler
1UCLA Optic Neuropathy Center, University of California, Los Angeles, USA.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|March 1, 1996
Summary
Optic disc filling delay is not characteristic of nonischemic optic disc edema, unlike nonarteritic anterior ischemic optic neuropathy (NAION). This finding helps differentiate NAION from papillitis using fluorescein angiography.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
- Medical Imaging
Background:
- Nonischemic optic disc edema can present with optic disc swelling.
- Differentiating causes of optic disc edema is crucial for appropriate management.
- Fluorescein angiography is a key diagnostic tool in evaluating optic neuropathies.
Purpose of the Study:
- To investigate the association between nonischemic optic disc edema and delayed optic disc filling on fluorescein angiography.
- To compare fluorescein angiographic findings in nonischemic optic disc edema with those in nonarteritic anterior ischemic optic neuropathy (NAION).
Main Methods:
- Fluorescein angiograms of patients with papillitis, papilledema, and cavernous hemangioma-related optic disc edema were analyzed.
- Optic disc filling times were compared to age-matched controls.
- Data were compared with historical and new cohorts of NAION patients (NAION and NAIONy).
Main Results:
- No significant delay in optic disc filling was observed in patients with nonischemic optic disc edema, including papillitis.
- Significant delays in optic disc filling were confirmed in both typical NAION and younger NAION patients (NAIONy).
- A 5-second delay in disc filling was absent in nonischemic optic disc edema but present in 76% of typical NAION and 62% of NAIONy cases.
Conclusions:
- Delayed optic disc filling is a hallmark of NAION, not nonischemic optic disc edema.
- Fluorescein angiography findings can assist in distinguishing NAION from papillitis.