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High-performance liquid chromatographic analysis of glycosaminoglycan-derived oligosaccharides
T Imanari1, T Toida, I Koshiishi
1Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Journal of Chromatography. A
|January 12, 1996
Abstract:
High-performance liquid chromatography of glycosaminoglycan (GAG)-derived oligosaccharides has been employed for the structural analysis and measurement of hyaluronan, chondroitin sulphate, dermatan sulphate, keratan sulphate, heparan sulphate and heparin. Recent developments in the separation and detection of unsaturated disaccharides and oligosaccharides derived from GAGs by enzymatic or chemical degradation are reviewed.