Related Experiment Video
Updated: Aug 14, 2026

10:34
Gene Delivery to Postnatal Rat Brain by Non-ventricular Plasmid Injection and Electroporation
Published on: September 18, 2010
Transgenesis in the rat and larger mammals
1Centre for Genome Research, The University of Edinburgh, United Kingdom.
The Journal of Clinical Investigation
|April 1, 1996
Abstract
No abstract available in PubMed .
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Overview
In-vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

