[Mapping the sequences, preferentially bound with the nuclear matrix, on human chromosome 19]

A plasmid library (400 clones) of the human chromosome 19 sequences selectively binding to nuclear matrix was obtained and characterized. Approximately 50% clones contained DNA sequences specific for human chromosome 19. Over 90% of these sequences represented matrix attachment regions (MARs). Eight MARs were localized to the chromosome 19 physical map.