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Cytogenetic abnormalities in 13 patients with multiple myeloma
1Laboratori de Citologia Hematològica, Unitat d'Hematologia i Oncologia1973, Hospital Central L'Aliança, Barcelona, Spain.
Cancer Genetics and Cytogenetics
|February 1, 1996
Abstract:
Cytogenetic analysis was successfully performed in 45 consecutive multiple myeloma (MM) patients. Cytogenetic abnormalities were observed in 13 of 45 patients (29%). Eleven patients showed numerical changes and 9 showed structural abnormalities in chromosomes 5, 9, 11, 14, 15, and 19 were most frequently gained. Structural abnormalities preferentially involved chromosomes 6, 13, and 14.