Depression and HIV. A nursing perspective on a complex relationship

This article (1) addresses current perspectives on depression as a psychobiologic condition, which in the case of major depression constitutes a bona fide disease state, (2) explores the complex relationship between HIV and depressive illness, and (3) addresses how this new knowledge serves to enhance nursing assessment and intervention in these persons diagnosed with HIV disease and concurrent depression. By attaining these three goals, the nursing clinician gains a broader perspective on depression and HIV.