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Updated: Sep 2, 2026

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
Published on: March 21, 2021
[Changes in the granula of type II pneumocytes corresponding to the oxygen content of the air]
Abstract:
The morphology of granula of type II-granulocytes from lungs of rabbits and rats was studied. In pneumocytes of rabbits dense bodies predominated with high lipoprotein content, whereas in rats the majority had lamellar structure. Under treatment with hyperbaric oxygen the granula showed increased lipoprotein content, suggesting that the emanation of the content of granula to the alveolar surface is inhibited. Under hypoxia the release from the granula was enhanced, and after 16 hours of hypoxia the amount of granula was decreased as well as their lipoprotein content.
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