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Mutations in tumour suppressor gene p53 in two feline fibrosarcomas
B Mayr1, G Schaffner, R Kurzbauer
1Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria.
The British Veterinary Journal
|November 1, 1995
Abstract:
Exons 5-7 of the tumour suppressor gene p53 were investigated in genomic DNA of tumours of domestic cats. In one fibrosarcoma investigated we observed a mutation GAG-->AAG (glutamic acid-->lysine) in codon 180; in another there was a mutation CGG-->TGG (arginine-->tryptophane) in codon 248.