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Trisomy 16 fetus surviving into the second trimester

W Cusick1, M Bork, B Fabri

  • 1Center for Human Reproduction, Division of Maternal-Fetal Medicine, Chicago, IL 60610, USA.

Prenatal Diagnosis
|November 1, 1995
PubMed

A 27-year-old gravida 4, para 3 was found to have anhydramnios at 14 weeks' gestation following a size/date discrepancy noted at her routine prenatal visit. A detailed ultrasound revealed multiple fetal anomalies including congenital heart defect, chest hypoplasia, and bilateral dysplastic kidneys. Karyotype revealed trisomy 16 in 15/15 cells from a tissue specimen obtained from the fetal cord insertion site following elective pregnancy termination.

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