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Related Experiment Videos

Intrasellar abscess following transsphenoidal surgery

M M Henegar1, M B Koby, D L Silbergeld

  • 1Department of Neurological Surgery, Washington University, St. Louis, Missouri, USA.

Surgical Neurology
|February 1, 1996
PubMed
Summary

Intrasellar abscesses, rare after pituitary surgery, demand prompt surgical drainage and antibiotics. Early diagnosis is critical to reduce high mortality rates associated with these post-surgical infections.

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Area of Science:

  • Neurosurgery
  • Endocrinology
  • Infectious Diseases

Background:

  • Intrasellar abscesses are rare complications following transsphenoidal surgery.
  • Literature reports only two previous cases of intrasellar abscess.
  • High mortality rates are associated with intrasellar abscesses, especially without surgical intervention.

Observation:

  • Two cases of intrasellar abscess post-transsphenoidal surgery are presented.
  • Patients presented with delayed symptoms, including expanding sellar mass and recurrent meningitis.
  • Abscesses occurred weeks to years after initially uncomplicated pituitary surgery.

Findings:

  • Surgical drainage, either transsphenoidal or transnasal endoscopic, is essential for treatment.
  • Antibiotic therapy is a crucial adjunct to surgical intervention.

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  • Successful outcomes were achieved with prompt diagnosis and treatment.

    • Implications:

    • Intrasellar abscess should be considered in the differential diagnosis for patients with meningitis or sellar mass expansion post-transsphenoidal surgery.
    • Aggressive management including surgical drainage is necessary to improve patient outcomes.
    • Further research into the incidence and prevention of these rare complications is warranted.