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Modification of the extracellular matrix following myocardial infarction monitored by FTIR spectroscopy
1Institute for Biodiagnostics, National Research Council Canada, Winnipeg, Manitoba.
Biochimica Et Biophysica Acta
|March 1, 1996
Abstract:
Comparison of mid- and near-infrared spectra of control and infarcted rat ventricular tissue reveals the presence of absorptions in infarcted tissue which are highly characteristics of collagen, indicating large scale deposition of type I collagen in the myocardium following infarction. These results demonstrate that IR spectroscopy may be used to rapidly monitor the modifications of the extracellular matrix associated with myocardial infarction.